The term brood is used to refer to the embryo or egg, the larva and the pupa stages in the life of holometabolous insects. The brood of honey bees develops within a bee hive. In man-made, removable frame hives, such as Langstroth hives, each frame which is mainly brood is called a brood frame. Brood frames usually have some pollen and nectar or honey in the upper corners of the frame. The rest of the brood frames cells may be empty or occupied by brood in various developmental stages.