- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice.
Industry:Medical
A congenital abnormality of the central nervous system marked by failure of the midline structures of the cerebellum to develop, dilation of the fourth ventricle, and upward displacement of the transverse sinuses, tentorium, and torcula. Clinical features include occipital bossing, progressive head enlargement, bulging of anterior fontanelle, papilledema, ataxia, gait disturbances, nystagmus, and intellectual compromise.
Industry:Medical
The process through which DNA is extracted from any of a number of possible cell sources and stored indefinitely by freezing or refrigerating for future testing; done when a specific test is not presently available or when the decision to have testing has not been made.
Industry:Medical
To reduce the complexity of (a chemical compound) by splitting off one or more groups or larger components (cellulose is degraded by the action of some bacteria). Intransitive verb: to undergo chemical degradation.
Industry:Medical
A gene alteration that causes or predisposes an individual to a specific disease.
Industry:Medical
The network of filaments, tubules, and interconnecting filamentous bridges which give shape, structure, and organization to the cytoplasm.
Industry:Medical
The length of a straight line that extends from one edge of an object, through its center and to the opposite edge. It is usually used to measure the size of round or spherical shapes.
Industry:Medical
1) Thickening and loss of elasticity of the coronary arteries, leading to progressive insufficiency of the arteries (coronary disease).
2) A condition and especially one caused by atherosclerosis that reduces the blood flow through the coronary arteries to the heart muscle and typically results in chest pain or heart damage -- called also coronary disease, coronary heart disease.
3) A disease in which there is a narrowing or blockage of the coronary arteries (blood vessels that carry blood and oxygen to the heart). Coronary heart disease is usually caused by atherosclerosis (a build up of fatty material and plaque inside the coronary arteries). The disease may cause chest pain, shortness of breath during exercise, and heart attacks. The risk of coronary heart disease is increased by having a family history of coronary heart disease before age 50, older age, smoking tobacco, high blood pressure, high cholesterol, diabetes, lack of exercise, and obesity.
Industry:Medical
1) Encompasses the mouth, esophagus, stomach, intestines, biliary tract, pancreas, liver, and associated hormones and secretions.
2) The organs that take in food and turn it into products that the body can use to stay healthy. Waste products the body cannot use leave the body through bowel movements. The digestive system includes the salivary glands, mouth, esophagus, stomach, liver, pancreas, gallbladder, small and large intestines, and rectum.
Industry:Medical
